Nonsteroidal components of the unsaponifiable fraction of human liver.

Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells.

The fatty acid composition of dietary oils can modulate the incorporation of triacylglycerol-rich lipoproteins (TRL) into hepatocytes, thus affecting the atherogenicity of these particles. However, nothing is known about the effect of the unsaponifiable fraction of the oils. In the present study, we evaluated the influence of these components on the uptake of TRL by rat primary hepatocytes. TRL...

The role of unsaponifiable components in the lipidemic property of olive oil.

Pure olive oil triglycerides (POLO), free from all unsaponifiable matter, were isolated from Virgin Spanish olive oil (COLO) by alumina-charcoal column chromatography. COLO and POLO were used as sources of dietary fat in two animal studies. The responses of serum and liver lipids to the two types of dietary fat were examined. Our results show that animals fed POLO-diet gave somewhat higher seru...

Lxxvii. the Unsaponifiable Fraction of Liver

Effect of minor components of virgin olive oil on topical antiinflammatory assays.

Interest in the health-promoting effects of virgin olive oil, an important part of the "Mediterranean diet", prompted us to determine the antiinflammatory effects of erythrodiol, beta-sitosterol and squalene, identified as major components of the so-called "unsaponifiable fraction" of virgin olive oil, as well as of the phenolic compounds from the "polar fraction": oleuropein, tyrosol, hydroxyt...

Studies of Sebum. II. Some constituents of the unsaponifiable matter of human sebum.

as one of the major constituents, accounting for about 16% of the unsaponifiable matter and about 35% of the hydrocarbon fraction. Some preliminary chemical tests were made for the fatsoluble vitamins, and the presence ofa small amount of vitamin E in human sebum was reported. A more complete study of the unsaponifiable matter has now been made, and this material has been more thoroughly examin...